Chorionic Villus Sampling
Chorionic Villus Sampling (CVS) is an advanced diagnostic prenatal test performed in early pregnancy to detect chromosomal and genetic disorders in the fetus. It provides definitive results much earlier than amniocentesis and helps parents make timely, informed decisions.
What Is Chorionic Villus Sampling (CVS)?
CVS involves collecting a small sample of placental tissue (chorionic villi) under continuous ultrasound guidance. These cells share the baby’s genetic makeup and are analyzed to detect chromosomal and genetic abnormalities.
When Is CVS Performed?
CVS is usually performed between 11 and 13 weeks of pregnancy, making it one of the earliest diagnostic tests available in prenatal care.
Who Is Advised CVS?
- High-risk First Trimester Screening or NIPS results
- Increased nuchal translucency (NT)
- Previous child with chromosomal or genetic disorder
- Parental carrier status for genetic diseases
How Is the CVS Procedure Performed?
CVS is performed under strict ultrasound guidance using either the transabdominal or transcervical approach, depending on placental position. A fine needle or catheter is used to gently collect placental tissue. The procedure takes only a few minutes and does not require hospital admission.
What Can CVS Detect?
- Down syndrome (Trisomy 21)
- Trisomy 13 and Trisomy 18
- Single gene disorders such as thalassemia
- Inherited metabolic and genetic diseases
How Accurate Is CVS?
It provides definitive results and is not a screening test. Very rarely placental cells might show different genetic makeup compared to the fetal cells (placental mosaicism). In these situations further confirmation with amniocentesis would be necessary.
Is CVS Safe?
When performed by an experienced fetal medicine specialist under ultrasound guidance, CVS is a safe procedure. The risk of miscarriage is low (less than 0.3%). All possible risks and benefits are explained in detail before the test. These risks are mitigated by appropriate post procedure precautions which are explained.
When Will the CVS Results Be Available?
Rapid preliminary results may be available within 48–72 hours for common chromosomal abnormalities. Final genetic reports typically take 2–3 weeks. Dr. Ashwini Rathi personally reviews and explains all results to the parents.
Why Choose Dr. Ashwini Rathi for CVS?
- MD, MRCOG qualified Fetal Medicine Specialist
- Extensive experience in ultrasound-guided fetal procedures
- High precision with maximum safety standards
- Complete pre- and post-test genetic counseling
- Ethical, patient-centered decision support
At Dr. Ashwini Rathi’s fetal medicine center, Chorionic Villus Sampling is performed with expert precision, advanced ultrasound guidance, and compassionate care to ensure the safest and most accurate early diagnosis.